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autismautistic spectrum disorderhead circumferencelabor inductionlabour inductionobstetric medicationpreeclampsiaRhesus-immunizationvalproate

Fetal valproate syndrome and autism: additional evidence of an association

Autor(en)

Williams G, King J, Cunningham M, Stephan M, Kerr B, Hersh JH, Dean JC

Veröffentlichungsdatum

2001

Ort der Sudie

USA

Abstract

The authors had previously reported on a patient whose clinical phenotype was compatible with both fetal valproate syndrome (FVS) and autism. Here they present five additional patients with FVS and autism. In all five of these patients, there was evidence of cognitive deficits, manifestations of autism, and typical phenotypic characteristics of FVS. The association between this known teratogen and autism has both clinical and research implications.

Diskussion

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