
Post-natal growth and health in children born after cryopreservation as embryos
Wennerholm U-B, Albertsson-Wikland K
1998
Sweden
255 children from cryopreserved embryos were matched by maternal age, parity, single or twin pregnancy and date of delivery, with 255 children born after IVF with fresh embryos, and 252 children from spontaneous pregnancies. The children were assessed at the age of 18 months. Growth features were similar for both singletons and twins in the three groups. There were 6 (2.4%) of 255, 9 (3.5%) of 255, and 8 (3.2%) of 252 major malformations in the cryopreserved group, sandard IVF, and spontaneous group respectively. The prevalence of chronic diseases did not differ between the three groups. The authors conclude that the cryopreservation process does not adversely affect the growth and health of children during infancy and early childhood.
For obvious reasons we need to wait several years to have the results of studies assessing such children after puberty. See also entries 0040, 0102 0118 and 0120.